CLASP2 anticorps (AA 1201-1294) (Biotin)

N° du produit ABIN891144

Cet anticorps anti-CLASP2 est un anticorps Lapin Polyclonal détectant CLASP2 dans WB, ELISA, IHC (p) et IHC (fro). Adapté pour Humain.

Aperçu rapide pour CLASP2 anticorps (AA 1201-1294) (Biotin) (ABIN891144)

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CLASP2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CLASP2 anticorps (Biotin)

Épitope: AA 1201-1294

Homologie: Human,Mouse,Rat,Dog,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CLASP2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur CLASP2

Antigène: CLASP2 (Cytoplasmic Linker Associated Protein 2 (CLASP2))

Autre désignation: CLASP2

Sujet:

Synonyms: CLASP 2, CLIP associating protein 2, Cytoplasmic linker associated protein 2, hOrbit2, KIAA0627, Multiple asters Mast like homolog 2, Protein Orbit homolog 2, CLAP2_HUMAN.

Background: CLASP2 is a microtubule plus end tracking protein that promotes the stabilization of dynamic microtubules and is required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. CLASP2 may act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3 kinase signaling. CLASP2 also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

ID gène: 23122

Pathways: Dynamique des Microtubules, Maintenance of Protein Location