e6/ ITGB4BP (AA 141-245) anticorps (Alexa Fluor 555)

N° du produit ABIN895129

Détail du produit

Antigène: e6/ ITGB4BP

Épitope: AA 141-245

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human eIF6

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: e6/ ITGB4BP

Autre désignation: e6/ITGB4BP

Sujet:

Synonyms: b2gcn, B2GCN homolog, B4 integrin interactor, Binding protein of beta-4 integrin, CAB, e-6, E3A, E6, Eukaryotic translation initiation factor 3A, Eukaryotic translation initiation factor 6, 6_HUMAN, ITGB4BP, OK/SW-cl.27, p27 beta 4 integrin binding protein, p27BBP, p27BBP, RP4-614O4.1.

Background: Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by Intergrin beta 4 binding protein binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding several different isoforms have been found for this gene.

ID gène: 3692