Estrogen Receptor alpha + beta (AA 201-300) anticorps (Alexa Fluor 555)

N° du produit ABIN895602

Détail du produit

Antigène: Estrogen Receptor alpha + beta

Épitope: AA 201-300

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Rat

Homologie: Mouse,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Estradiol Receptor alpha + beta

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Estrogen Receptor alpha + beta

Sujet:

Synonyms: Estrogen Receptor alpha/beta, Atherosclerosis, susceptibility to, included, DKFZp686N23123, ER Alpha, ER, ER Beta, ER-alpha, ER-beta, ER[a], ER[b], Era, ERalpha, Erb, Erb2, ERbeta, ESR, ESR BETA, ESR1, ESR1_HUMAN, ESR2, ESRA, ESRB, Estr, Estra, Estradiol Receptor alpha, Estradiol receptor, Estradiol Receptor beta, ESTRB, Estrogen receptor 1 alpha, Estrogen Receptor 1, Estrogen receptor 2 ER beta, Estrogen Receptor 2, Estrogen receptor 2 ER beta, Estrogen receptor alpha, Estrogen receptor, Estrogen receptor beta 4, Estrogen resistance, included, HDL cholesterol, augmented response of, to hormone replacement, included, Myocardial infarction, susceptibility to, included, NR3A1, NR3A2, Nuclear receptor subfamily 3 group A member 1, Nuclear receptor subfamily 3 group A member 2, OTTHUMP00000017718, OTTHUMP00000017719, RNESTROR.

Background: The estrogen receptor (ER) is a 66 kDa protein that mediates the actions of estrogens in estrogen responsive tissues. It is a member of a large superfamily of nuclear hormone receptors that function as ligand activated transcription factors. The ER gene consists of more than 140 kb of genomic DNA divided into 8 exons. These translate into a protein with six functionally discrete domains, labeled A through F. A second form of the estrogen receptor, ER beta has recently been described. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti estrogen (e.g. tamoxifen) therapy.

ID gène: 2099, 2100