ERCC6L anticorps (AA 301-400) (Alexa Fluor 488)

N° du produit ABIN895648

Détail du produit anti-ERCC6L anticorps (Alexa Fluor 488)

Antigène: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Épitope: AA 301-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC6L est conjugé à/à la Alexa Fluor 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human ERCC6L

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ERCC6L

Antigène: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Autre désignation: ERCC6L (ERCC6L Produits)

Synonymes: anticorps PICH, anticorps RAD26L, anticorps BC004701, anticorps D330021P09Rik, anticorps RGD1565734, anticorps fc22h03, anticorps si:ch211-278b8.3, anticorps wu:fc22h03, anticorps ERCC excision repair 6 like, spindle assembly checkpoint helicase, anticorps excision repair cross-complementing rodent repair deficiency complementation group 6 like, anticorps DNA excision repair protein ERCC-6-like, anticorps excision repair cross-complementation group 6-like, anticorps ERCC6L, anticorps Ercc6l, anticorps LOC100373376, anticorps LOC100494766, anticorps LOC100552957, anticorps LOC100560751, anticorps LOC100563247, anticorps ercc6l

Sujet:

Synonyms: ATP dependent helicase ERCC6 like, DNA excision repair protein ERCC 6 like, ERCC 6L, ERCC6L, Excision repair cross complementing rodent repair deficiency complementation group 6 like, Excision repair protein ERCC6 like, FLJ20105, MGC131695, PICH, Plk1 interacting checkpoint helicase, SNF2/RAD54 family protein, Tumor antigen BJ HCC 15, ERC6L_HUMAN.

Background: ERCC6L belongs to the SNF2 ATPase family and acts as an essential component of the spindle assembly checkpoint. It contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. It acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. ERCC6L may also play a role in the teratogenic action of alcohol.

ID gène: 54821