HSPB6 anticorps (AA 6-80) (Alexa Fluor 350)

N° du produit ABIN901421

Détail du produit anti-HSPB6 anticorps (Alexa Fluor 350)

Antigène: HSPB6 (Heat Shock Protein, alpha-Crystallin-Related, B6 (HSPB6))

Épitope: AA 6-80

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPB6 est conjugé à/à la Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human HSP20

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur HSPB6

Antigène: HSPB6 (Heat Shock Protein, alpha-Crystallin-Related, B6 (HSPB6))

Autre désignation: Hsp20 (HSPB6 Produits)

Synonymes: anticorps Hsp20, anticorps p20, anticorps AA387366, anticorps Gm479, anticorps HSP20, anticorps heat shock protein family B (small) member 6, anticorps heat shock protein, alpha-crystallin-related, B6, anticorps heat shock protein family B (small) member 6 L homeolog, anticorps heat shock protein, alpha-crystallin-related, b6, anticorps HSPB6, anticorps Hspb6, anticorps hspb6.L, anticorps hspb6

Sujet:

Synonyms: Heat Shock Protein 20, FLJ32389, Heat shock 20 kDa like protein p20, Heat shock protein alpha crystallin related B6, Heat shock protein beta 6, Hspb6, HSPB6_HUMAN.

Background: Hsp20 is a small heat shock protein related to Hsp25, Hsp27 and may form different hetercomplexes with these proteins. The specific physiological function of Hsp20 is not yet known. It is distributed ubiquitously in tissues, but is found in higher levels in skeletal, smooth and heart muscle. Under normal conditions, Hsp20 is diffusely distributed in the cytosol, but under heat stress conditions, it translocates to the nucleus. Unlike other heat shock proteins the amount of Hsp20 does not increase after heat shock. The Hsp20 was demonstrated to constitute up to 1.3 % of the total cellular protein in vertebrate tissues, especially in muscle, and its expression is related to muscle contraction, specifically in slow-twitch muscle. Hsp20 may form different heterocomplexes with other Hsp's, such as alpha-crystalline and Hsp25. Phosphorylated form of Hsp20 is proposed to interact with monomeric actin whereas dephosphorylated form binds polymeric actin filaments. In normal conditions Hsp20 is diffusely disturbed in cytosol but under the heat stress it undergoes translocation to membrane fraction.

ID gène: 126393