ITGAV/ITGB1 anticorps (PE-Cy5.5)

N° du produit ABIN902943

Détail du produit anti-ITGAV/ITGB1 anticorps (PE-Cy5.5)

Antigène: ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))

Reactivité: Humain, Souris, Rat, Porc, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ITGAV/ITGB1 est conjugé à/à la PE-Cy5.5

Application: Western Blotting (WB), Flow Cytometry (FACS)

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogène: Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1

Isotype: IgG

Information d'application

Indications d'application: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur ITGAV/ITGB1

Antigène: ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))

Abstract: ITGAV/ITGB1 Produits

Sub Type: Cocktail

Sujet:

Synonyms: Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29

Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).

Poids moléculaire: 114kDa

ID gène: 3685, 3688