PIWIL1 anticorps (AA 551-650) (Alexa Fluor 555)

N° du produit ABIN911197

Détail du produit anti-PIWIL1 anticorps (Alexa Fluor 555)

Antigène: PIWIL1 (Piwi-Like 1 (PIWIL1))

Épitope: AA 551-650

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIWIL1 est conjugé à/à la Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Humain, Souris

Homologie: Rat,Chicken

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from chicken PIWIL1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PIWIL1

Antigène: PIWIL1 (Piwi-Like 1 (PIWIL1))

Autre désignation: PIWIL1 (PIWIL1 Produits)

Synonymes: anticorps ziwi, anticorps PIWI, anticorps HIWI, anticorps MIWI, anticorps piwi like RNA-mediated gene silencing 1, anticorps PIWI-like protein 1, anticorps putative PIWI-like protein 1, anticorps putative argonaut-like protein, anticorps piwi-like RNA-mediated gene silencing 1, anticorps PIWIL1, anticorps Tb10.70.5520, anticorps LINJ_21_0470, anticorps LBRM_21_0470, anticorps piwil1, anticorps Piwil1

Sujet:

Synonyms: PIWI, Piwi-like protein 1, PIWIL1

Background: Plays a central role during gametogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 3 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation (By similarity).

ID gène: 416804

UniProt: A6N7Y9