Pp1a/Pp2ca/Ppp1ca (AA 281-382) anticorps (Alexa Fluor 350)

N° du produit ABIN911758

Détail du produit

Antigène: Pp1a/Pp2ca/Ppp1ca

Épitope: AA 281-382

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Réactivité croisée: Souris

Homologie: Human,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human PPP1CA

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Pp1a/Pp2ca/Ppp1ca

Sujet:

Synonyms: PP 1A, PP1A, PP2C ALPHA, PP2CA, PPP1CA, Protein Phosphatase 2C Alpha Isoform, Serine threonine protein phosphatase PP1 alpha catalytic subunit, EC 3.1.3.16, MGC15877, MGC1674, MGC9201.

Background: PPP1A is a serine/threonine protein phosphatase catalytic subunit that is essential for regulating cellular stress responses in eukaryotes. It binds to magnesium or manganese ions and exists as a monomer. It is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. PPP1A is involved in the regulation long term synaptic plasticity and may play an important role in dephosphorylating substrates such as Ca2+/calmodulin dependent protein kinase II.

ID gène: 5499

UniProt: P62136