TLR4 anticorps (N-Term)

N° du produit ABIN920639

L’anticorps anti-TLR4 Polyclonal Lapin est utilisé pour la détection de TLR4 dans des échantillons de Humain. Il a été validé pour WB et ICC.

Aperçu rapide pour TLR4 anticorps (N-Term) (ABIN920639)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TLR4 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Détail du produit anti-TLR4 anticorps

Épitope: N-Term

Attributs du produit: Positive Control: Located in the membrane and highly expressed in placenta, spleen and peripheral blood leukocytes. Detected in monocytes, macrophages, dendritic cells and several types of T-cells.

Purification: Antigen Immunoaffinity purified

Immunogène: Rabbit polyclonal TLR4 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of TLR4.

Isotype: IgG

Information d'application

Indications d'application: Western blot: use at 2-5 µg/mL

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.02% sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TLR4

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Sujet: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Studies with TLR4 deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram- negative sepsis. Synonyms:

Poids moléculaire: 95 kDa

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins