GALR2 anticorps (C-Term)

N° du produit ABIN926733

Détail du produit anti-GALR2 anticorps

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GALR2 est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: GALR2 antibody was raised in rabbit using the C terminal of GALR2 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

GALR2 Blocking Peptide, catalog no. 33R-10391, is also available for use as a blocking control in assays to test for specificity of this GALR2 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur GALR2

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Autre désignation: GALR2 (GALR2 Produits)

Synonymes: anticorps GALNR2, anticorps mGalR, anticorps GALR2, anticorps GAL2-R, anticorps GALR-2, anticorps galanin receptor 2, anticorps transcription regulator. LacI family, raffinose related, anticorps DNA-binding transcriptional regulator GalR, anticorps galactose operon repressor, anticorps galanin receptor type 2, anticorps GALR2, anticorps Galr2, anticorps LOC100037698, anticorps rafR, anticorps galR2, anticorps LOC103690156

Sujet: Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. Synonyms: Polyclonal GALR2 antibody, Anti-GALR2 antibody, galanin receptor 2 antibody, GALNR2 antibody, MGC125983 antibody, MGC125984 antibody.

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour