TRAF1 anticorps (Middle Region)

N° du produit ABIN926936

L’anticorps Lapin Polyclonal anti-TRAF1 a été validé pour WB. Il convient pour détecter TRAF1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour TRAF1 anticorps (Middle Region) (ABIN926936)

Antigène: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRAF1 anticorps

Épitope: Middle Region

Réactivité croisée: Souris, Rat (Rattus), Boeuf (Vache), Chien, Poisson zebré (Brachydanio rerio)

Purification: Purified

Immunogène: TRAF1 antibody was raised in rabbit using the middle region of TRAF1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TRAF1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this TRAF1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TRAF1

Antigène: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Autre désignation: TRAF1

Sujet: This protein is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from various receptors of the TNFR superfamily. This protein and TRAF2 form a heterodimeric complex, which is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF2 also interacts with inhibitor-of-apoptosis proteins (IAPs), and thus mediates the anti-apoptotic signals from TNF receptors. The expression of this protein can be induced by Epstein-Barr virus (EBV). EBV infection membrane protein 1 (LMP1) is found to interact with this and other TRAF proteins, this interaction is thought to link LMP1-mediated B lymphocyte transformation to the signal transduction from TNFR family receptors. Synonyms: Polyclonal TRAF1 antibody, Anti-TRAF1 antibody, TNF receptor-associated factor 1 antibody, EBI6 antibody, MGC:10353 antibody.

Pathways: Signalisation NF-kappaB, Apoptose, Cell-Cell Junction Organization, Asymmetric Protein Localization