STAT5B anticorps (N-Term)

N° du produit ABIN927756

Cet anticorps anti-STAT5B Polyclonal Lapin (ABIN927756) détecte spécifiquement STAT5B dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Poisson zèbre (Danio rerio), Poulet et Xenopus laevis.

Aperçu rapide pour STAT5B anticorps (N-Term) (ABIN927756)

Antigène: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc, Poisson zèbre (Danio rerio), Poulet, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAT5B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-STAT5B anticorps

Épitope: N-Term

Réactivité croisée: Souris, Rat (Rattus), Poulet, Porc, Boeuf (Vache), Chien, Poisson zebré (Brachydanio rerio), Grenouille

Purification: Purified

Immunogène: STAT5 B antibody was raised in rabbit using the N terminal of STAT5 as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

STAT5B Blocking Peptide, (ABIN937008), is also available for use as a blocking control in assays to test for specificity of this STAT5B antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur STAT5B

Antigène: STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))

Autre désignation: STAT5B

Sujet: The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. Synonyms: Polyclonal STAT5B antibody, Anti-STAT5B antibody, signal transducer and activator of transcription 5B antibody, STAT5 antibody.

Pathways: Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation