Integrin Alpha2b anticorps (Biotin)

N° du produit ABIN94107

Cet anticorps anti-Integrin Alpha2b est un anticorps Souris Monoclonal détectant Integrin Alpha2b dans FACS. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour Integrin Alpha2b anticorps (Biotin) (ABIN94107)

Antigène: Integrin Alpha2b (CD41)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin Alpha2b est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: MEM-06

Détail du produit anti-Integrin Alpha2b anticorps (Biotin)

Fonction: Anti-Hu CD41 Biotin

Specificité: The antibody MEM-06 reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 kDa) and GPIIb beta (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.

Réactivité croisée (Details): Human

Purification: Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.

Immunogène: Leukocytes of patient suffering from LGL-type leukaemia.

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 2 μg/mL.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.
Avoid prolonged exposure to light.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Références pour anticorps anti-Integrin Alpha2b (Biotin) (ABIN94107)

Karimi, Dalirfardouei, Dias, Lötvall, Lässer: "Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma - Contributions of platelet extracellular vesicles in plasma samples." dans: Journal of extracellular vesicles, Vol. 11, Issue 5, pp. e12213, (2022) (PubMed).

Détails sur Integrin Alpha2b

Antigène: Integrin Alpha2b (CD41)

Autre désignation: CD41

Sujet: Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,Platelet GPIIb, Integrin alpha-IIb, GPalpha IIb, GTA

ID gène: 3674

UniProt: P08514

Pathways: Integrin Complex