ADIPOQ anticorps

N° du produit ABIN950284

Détail du produit anti-ADIPOQ anticorps

Antigène: ADIPOQ (Adiponectin (ADIPOQ))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp ADIPOQ est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects Mouse Adiponectin. It is crossreactive to Human Adiponectin protein in Western blotting.

Purification: Protein A/G Affinity Chromatography

Stérilité: 0.2 μm filtered

Immunogène: Purified Mouse Recombinant Adiponectin.

Clone: 7J61

Isotype: IgG2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL

Buffer: 0.2 μm filtered solution in PBS

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 months.

Date de péremption: 6 months

Détails sur ADIPOQ

Antigène: ADIPOQ (Adiponectin (ADIPOQ))

Autre désignation: Adiponectin (ADIPOQ Produits)

Synonymes: anticorps ADP, anticorps DCAF9, anticorps 6720489L24Rik, anticorps 9330209L04Rik, anticorps Adp, anticorps Mamdc1, anticorps RNSVSP4U, anticorps SVSIV1, anticorps Svp4, anticorps ACDC, anticorps ACRP30, anticorps ADIPQTL1, anticorps ADPN, anticorps APM-1, anticorps APM1, anticorps GBP28, anticorps apM-1, anticorps 30kDa, anticorps APN, anticorps Acdc, anticorps Acrp30, anticorps Ad, anticorps adipo, anticorps apM1, anticorps ADN, anticorps acrpl, anticorps adipo-b, anticorps adipoql, anticorps zgc:153584, anticorps adipoq, anticorps WD and tetratricopeptide repeats 1, anticorps MAM domain containing glycosylphosphatidylinositol anchor 2, anticorps seminal vesicle secretory protein 4, anticorps adiponectin, C1Q and collagen domain containing, anticorps adiponectin, C1Q and collagen domain containing, b, anticorps adiponectin, C1Q and collagen domain containing L homeolog, anticorps WDTC1, anticorps Mdga2, anticorps Svs4, anticorps ADIPOQ, anticorps Adipoq, anticorps adipoqb, anticorps adipoq.L

Sujet: Adiponectin, also known as Acrp30, is an adipocyte-derived protein with wide ranging paracrine and endocrine effects on metabolism and inflammation. It promotes adipocyte differentiation, fatty acid catabolism, and insulin sensitivity, and is negatively correlated with obesity, type 2 diabetes, and atherogenesis. In this context, adiponectin is an antiinflammatory agent, but it exerts proinflammatory effects in nonmetabolic disorders such as rheumatoid arthritis and inflammatory bowel disease. Adiponectin interacts with the receptors AdipoR1 and AdipoR2, calreticulin, and Cadherin13/ T-Cadherin, as well as with several growth factors. Mature mouse adiponectin consists of a 66 amino acid (aa) N-terminal collagenous region and a 137 aa C terminal C1q like globular domain which can be cleaved by a leukocytederived elastase. Mature mouse adiponectin shares 83 % and 91 % amino acid (aa) sequence identity with human and rat adiponectin, respectively. Adiponectin associates into trimers that may assemble into medium molecular weight (MMW) hexamers and then into >300 kDa high molecular weight (HMW) oligomers. The glycosylation of four hydroxylated lysine residues in the collagenous domain is required for the intracellular formation of HMW complexes. The various multimeric forms of adiponectin exhibit distinct tissue specific and gender specific profiles and activities.Synonyms: 30 kDa adipocyte complement-related protein, ACDC, ACRP30, ADIPOQ, APM1, Adipocyte, Adipocyte complement-related 30 kDa protein, Adipose most abundant gene transcript 1 protein, C1q and collagen domain-containing protein, GBP28, Gelatin-binding protein

ID gène: 11450

NCBI Accession: NP_033735

UniProt: Q60994