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alpha Fetoprotein anticorps

AFP Reactivité: Humain IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN950378
  • Antigène Voir toutes alpha Fetoprotein (AFP) Anticorps
    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
    Reactivité
    • 233
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    Humain
    Hôte
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    Lapin
    Clonalité
    • 151
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    Polyclonal
    Conjugué
    • 135
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    Cet anticorp alpha Fetoprotein est non-conjugé
    Application
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    Recognizes Alpha-fetoprotein (AFP).
    Cellular Localization: Cytoplasmic.
    Purification
    Purified
    Immunogène
    Human Alpha-Fetoprotein purified from Human cord serum
    Top Product
    Discover our top product AFP Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
    Abstract
    AFP Produits
    Synonymes
    anticorps FETA, anticorps HPAFP, anticorps alpha fetoprotein, anticorps alpha-fetoprotein, anticorps AFP, anticorps Afp
    Sujet
    This is a major plasma protein produced by the yolk sac and the liver during fetal life. alpha Fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha Fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha Fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. alpha Fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha Fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasm, especially yolk sac tumors.Synonyms: Alpha-1-fetoprotein, Alpha-fetoglobulin, HPAFP
    ID gène
    20371
    NCBI Accession
    NP_001186276
    UniProt
    P02771
    Pathways
    C21-Steroid Hormone Metabolic Process
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