CAD anticorps (Middle Region)

N° du produit ABIN950999

Détail du produit anti-CAD anticorps

Antigène: CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))

Épitope: AA 787-816, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CAD est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to CAD.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 787-816 amino acids from the Central region of human CAD

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CAD

Antigène: CAD (Carbamoyl-Phosphate Synthetase 2, Aspartate Transcarbamylase, and Dihydroorotase (CAD))

Autre désignation: CAD Protein (CAD Produits)

Synonymes: anticorps Cpad, anticorps AU018859, anticorps 2410008J01Rik, anticorps cb456, anticorps wu:fc30c12, anticorps wu:fc33d01, anticorps wu:fc67g02, anticorps si:dkey-221h15.3, anticorps CAD, anticorps xcad, anticorps carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase, anticorps CAD, anticorps Cad, anticorps cad

Sujet: The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides.Synonyms: ACTase, Aspartate carbamoyltransferase, DHOase, Dihydroorotase, GATase, Glutamine-dependent carbamoyl-phosphate synthase

Poids moléculaire: 242984 Da

ID gène: 790

NCBI Accession: NP_004332

Pathways: Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process