KDELR2 anticorps (C-Term)

N° du produit ABIN953024

Détail du produit anti-KDELR2 anticorps

Antigène: KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))

Épitope: AA 182-211, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KDELR2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes Human KDEL Receptor 2 / KDELR2 (C-term).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 182-211 amino acids from the C-terminal region of human KDELR2

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur KDELR2

Antigène: KDELR2 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))

Autre désignation: KDEL Receptor 2 / KDELR2 (KDELR2 Produits)

Synonymes: anticorps kdelr2, anticorps ELP-1, anticorps ERD2.2, anticorps 1110007A14Rik, anticorps kdelr1-a, anticorps KDEL endoplasmic reticulum protein retention receptor 2 L homeolog, anticorps KDEL endoplasmic reticulum protein retention receptor 2, anticorps KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2, anticorps KDEL endoplasmic reticulum protein retention receptor 1 L homeolog, anticorps kdelr2.L, anticorps KDELR2, anticorps Kdelr2, anticorps kdelr1.L

Sujet: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83 % identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq].Synonyms: ELP-1, ER lumen protein retaining receptor 2, ERD2-like protein 1, ERD2.2, KDEL endoplasmic reticulum protein retention receptor 2

Poids moléculaire: 24422 Da

ID gène: 11014

NCBI Accession: NP_001094073

Pathways: Maintenance of Protein Location