PLGF anticorps (AA 24-158)

N° du produit ABIN954169

Détail du produit anti-PLGF anticorps

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Épitope: AA 24-158

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLGF est non-conjugé

Application: Western Blotting (WB)

Specificité: Recognizes PlGF.

Réactivité croisée (Details): Species reactivity (tested):Mouse.

Purification: Protein A Chromatography

niveau d'endotoxine: < 0.1 EU/1 μg of the antibody (LAL)

Immunogène: Highly pure (>95%) recombinant Mouse PlGF (Ala24-Pro158) derived from Sf9 insect cells.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Reconstitution: Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2

Stock: 4 °C/-20 °C

Stockage commentaire: The lyophilized antibody is stable at RT for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C. Avoid repeated freeze-thaw cycles!

Date de péremption: 6 months

Références pour anticorps anti-PLGF (ABIN954169)

Bader, Hsu: "Inactivation of the tumor suppressor gene von Hippel-Lindau (VHL) in granulocytes contributes to development of liver hemangiomas in a mouse model." dans: BMC cancer, Vol. 16, Issue 1, pp. 797, (2017) (PubMed).

Détails sur PLGF

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Autre désignation: Placenta Growth Factor / PGF (PGF Produits)

Synonymes: anticorps D12S1900, anticorps PGFL, anticorps PLGF, anticorps PlGF-2, anticorps SHGC-10760, anticorps AI854365, anticorps PIGF, anticorps Plgf, anticorps PlGF, anticorps placental growth factor, anticorps placenta growth factor, anticorps PGF, anticorps Pgf, anticorps PLGF

Sujet: Placenta growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family of growth factors. PlGF and VEGF share primary structural as well as limited amino acid sequence homology with the A and B chains of PDGF. All eight cysteine residues involved in intra and interchain disulfides are conserved among these growth factors. As a result of alternative splicing, three PlGF RNAs encoding monomeric human PlGF1, PlGF2 and PlGF3 isoform precursors containing 149, 179 and 219 amino acid residues, respectively, have been described. In normal mouse tissues, only one mouse PlGF mRNA encoding the equivalent of human PlGF2 has been identified. Mouse PlGF shares 65 % amino acid identity with human PlGF2. The gene for PlGF has been mapped to mouse chromosome 12 and human chromosome 14. PlGF binds with high affinity to Flt1, but not to Flk1/KDR.Synonyms: PGFL, PLGF, PlGF

ID gène: 18654

NCBI Accession: NP_032853

Pathways: VEGFR1 Specific Signals