anticorps PEZ, anticorps PTP36, anticorps C130080N23Rik, anticorps OTTMUSG00000022087, anticorps protein tyrosine phosphatase, non-receptor type 14, anticorps PTPN14, anticorps Ptpn14
Sujet
The protein encoded by the PTPN14 gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.Synonyms: PTP36, PTPD2, Protein-tyrosine phosphatase pez, Tyrosine-protein phosphatase non-receptor type 14