PTPN22 anticorps (C-Term)

N° du produit ABIN954376

Détail du produit anti-PTPN22 anticorps

Antigène: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Épitope: AA 662-691, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN22 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes PTPN22 at C-term.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Purified through a Protein A column followed by peptide affinity purification

Immunogène: Synthetic peptide - KLH conjugated - corresponding to the C-terminal region (between 662-691aa) of human PTPN22.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PTPN22

Antigène: PTPN22 (Tyrosine-Protein Phosphatase Non-Receptor Type 22 (PTPN22))

Autre désignation: PTPN22 (PTPN22 Produits)

Synonymes: anticorps 70zpep, anticorps PEP, anticorps Ptpn8, anticorps LYP, anticorps LYP1, anticorps LYP2, anticorps PTPN8, anticorps protein tyrosine phosphatase, non-receptor type 22 (lymphoid), anticorps protein tyrosine phosphatase, non-receptor type 22, anticorps Ptpn22, anticorps PTPN22

Sujet: The PTPN22 gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.Synonyms: Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP, LYP1, LYP2, LyP, Lymphoid phosphatase, PEP, PTPN8, Tyrosine-protein phosphatase non-receptor type 22

ID gène: 26191

NCBI Accession: NP_001180360