PTPRN anticorps

N° du produit ABIN954381

Détail du produit anti-PTPRN anticorps

Antigène: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PTPRN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody recognizes PTPRN

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein A Chromatography

Immunogène: Recombinant protein.

Clone: 8-00E-003

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PTPRN

Antigène: PTPRN (Protein Tyrosine Phosphatase, Receptor Type, N (PTPRN))

Autre désignation: PTPRN (PTPRN Produits)

Synonymes: anticorps IA-2, anticorps IA-2/PTP, anticorps IA2, anticorps ICA512, anticorps R-PTP-N, anticorps mIA-A, anticorps mKIAA4064, anticorps Ia-2, anticorps fc43c04, anticorps ptprn, anticorps wu:fc43c04, anticorps ia-2, anticorps ia2, anticorps ica512, anticorps r-ptp-n, anticorps protein tyrosine phosphatase, receptor type N, anticorps protein tyrosine phosphatase, receptor type, N, anticorps protein tyrosine phosphatase, receptor type, Na, anticorps protein tyrosine phosphatase, receptor type N L homeolog, anticorps PTPRN, anticorps Ptprn, anticorps ptprna, anticorps ptprn.L

Sujet: IA-2, a R8 receptor protein tyrosine phosphatase, is one of the major autoantigens in type 1 diabetes. Autoantibodies against IA-2 have been detected in large numbers newly diagnosed patients with type 1 diabetes and appear to identify a subgroup of prediabetic subjects who rapidly progress to type 1 diabetes, however, IA-2 polymorphisms do not appear to be associated with type 1 diabetes. Three alternative spliced variants of IA-2 have been documented and alternative splicing of IA-2 gene has been suggested to be a permissive genetic mechanism for autoimmunity against the IA-2 type 1 diabetes autoantigen.Synonyms: ICA3, ICA512, Islet cell antigen 512, PTP IA-2, R-PTP-N, Receptor-type tyrosine-protein phosphatase-like N

ID gène: 5798

NCBI Accession: NP_002837

UniProt: Q16849