SNTB2 anticorps (Middle Region)
Aperçu rapide pour SNTB2 anticorps (Middle Region) (ABIN955046)
Antigène
Voir toutes SNTB2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 216-245, Middle Region
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Specificité
- This antibody detects human Syntrophin-3 / SNTB2.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Purification
- Purified through a protein A column,; followed by peptide affinity purification.
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Immunogène
- Synthetic peptide - KLH conjugated - corresponding to the central region (between 216-245aa) of human Syntrophin-3 / SNTB2.
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) Sodium Azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SNTB2 (Syntrophin, beta 2 (Dystrophin-Associated Protein A1, 59kDa, Basic Component 2) (SNTB2))
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Autre désignation
- Syntrophin-3 / SNTB2
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Sujet
- Syntrophins are structurally related proteins located at the neuromuscular synapse and play an important role in dystrophin associated protein (DAP) complex formation. To date there have been three distinct syntrophin isoforms discovered: alpha 1, beta 1, and beta 2. These proteins each contain a PDZ domain, a syntrophin-unique domain (SU), and three pleckstrin homology domains (PH1a,1b and 2). The PDZ domain has been shown to be responsible for binding syntrophin to nNOS and the DAP complex. This association results in localization of the nicotinic acetylcholine receptor to the cytoskeleton via the (S/T)XV C terminus.Synonyms: 59 kDa dystrophin-associated protein A1 basic component 2, Beta-2-syntrophin, SNT2B2, SNT3, SNTL, Syntrophin-like
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ID gène
- 6645
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NCBI Accession
- NP_006741
Antigène
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