anticorps TAFI48, anticorps mTAFI48, anticorps MGC:17061, anticorps RAFI48, anticorps SL1, anticorps TATA-box binding protein associated factor, RNA polymerase I, A, anticorps TATA-box binding protein associated factor, RNA polymerase I subunit A, anticorps Taf1a, anticorps TAF1A
Sujet
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the smallest SL1-specific TAF. Two transcripts encoding different isoforms have been identified.Synonyms: TAFI48, TATA box-binding protein-associated factor RNA polymerase I subunit A, TBP-associated factor 1A, TBP-associated factor RNA polymerase I 48 kDa, Transcription factor SL1