TMED6 anticorps (Middle Region)

N° du produit ABIN955245

Détail du produit anti-TMED6 anticorps

Antigène: TMED6 (Transmembrane Emp24 Protein Transport Domain Containing 6 (TMED6))

Épitope: AA 124-153, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMED6 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects TMED6 (Center).

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A column followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 124-153 amino acids from the Central region of human TMED6

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer.

Détails sur TMED6

Antigène: TMED6 (Transmembrane Emp24 Protein Transport Domain Containing 6 (TMED6))

Autre désignation: TMED6 (TMED6 Produits)

Synonymes: anticorps PRO34237, anticorps SPLL9146, anticorps 1810015P03Rik, anticorps 1810018I24Rik, anticorps transmembrane p24 trafficking protein 6, anticorps TMED6, anticorps Tmed6

Sujet: TMED6 (transmembrane emp24 domain-containing protein 6) is a 240 amino acid single-pass type I membrane protein that belongs to the EMP24/GP25L family and contains one GOLD domain. The gene that encodes TMED6 contains around 8,564 bases and maps to human chromosome 16q22.1. Encoding over 900 genes and consisting of approximately 90 million base pairs, chromosome 16 makes up nearly 3 % of the human genome and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, when mutated, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Alterations in the CREB gene and NOD2 gene, both of which are located on chromosome 16, result in Rubinstein-Taybi syndrome and Crohn's disease, respectively. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier.Synonyms: Transmembrane emp24 domain-containing protein 6, UNQ9146/PRO34237

ID gène: 146456

NCBI Accession: NP_653277