TLR4 anticorps (FITC)

N° du produit ABIN956803

Cet anticorps Souris Monoclonal détecte spécifiquement TLR4 dans FACS. Il présente une réactivité envers Humain et Chien.

Aperçu rapide pour TLR4 anticorps (FITC) (ABIN956803)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivité: Humain, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR4 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: HTA125

Détail du produit anti-TLR4 anticorps (FITC)

Specificité: This recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 Molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS.

Purification: Protein G purified

Immunogène: This antibody was developed by immunizing mice with Ba/F3 cell line expressing human TLR4 cell surface antigen (9).

Type of Immunogen: Cells

Isotype: IgG2a kappa

Information d'application

Indications d'application: Approved: Flo (0.5 - 1 μg/10 x10⁶)

Usage: Flow: Cell Surface, Intracellular. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM Tris, 150 mM sodium chloride, 0.05 % BSA, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze! Sensitive to light.

Stock: 4 °C

Stockage commentaire: Maybe stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4°C. Protect from light.

Détails sur TLR4

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Autre désignation: TLR4

Sujet: Name/Gene ID: TLR4
Family: Toll-like Receptor

Synonyms: TLR4, CD284, CD284 antigen, Homolog of Drosophila toll, TLR-4, TOLL, ARMD10, Toll-like receptor 4, HToll

ID gène: 7099

UniProt: O00206

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins