F12 anticorps

N° du produit ABIN957858

Détail du produit anti-F12 anticorps

Antigène: F12 (Coagulation Factor XII (F12))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp F12 est non-conjugé

Application: Immunodiffusion (ID)

Specificité: Human F12 / Factor XII. The defined antibody reactivity is restricted to FXII, FXIIa and complexes of FXIIa with other proteins. In immunoelectrophoresis, bi-dimensional electrophoresis and radial immunodiffusion (Ouchterlony) against normal plasma, a single precipitin line is obtained which shows a reaction of identity with precipitated purified Factor XII. No reaction is obtained with FXII-depleted plasma. Cross-reactivity The antiserum does not cross-react with any other human plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiserum has not been tested in detail, however in immunoelectrophoresis a reaction with Rhesus monkey plasma has been found.

Purification: Immunoaffinity absorbed

Immunogène: Human Factor XII

Type of Immunogen: Purified protein

Information d'application

Indications d'application: Approved: ID

Usage: This antiserum is primarily intended for the measurement of Factor XII in human plasma using the EID-method (Laurell): a specially purified agarose solution containing between 1 and 2 % antiserum is poured onto a glass plate and allowed to gel. Plasma containing FXII is incorporated into a series of wells and electrophoresis is performed. Rockets due to antigen/antibody reaction are measured. The height of the rocket is directly proportional to the FXII concentration in the plasma.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Sterile distilled water 1 ml

Concentration: Lot specific

Buffer: Lyophilized antiserum

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Long term: -20°C
Short term: +4°C. Avoid repeat freeze-thaw cycles.

Détails sur F12

Antigène: F12 (Coagulation Factor XII (F12))

Autre désignation: F12 / Factor XII (F12 Produits)

Synonymes: anticorps HAE3, anticorps HAEX, anticorps HAF, anticorps FXII, anticorps coagulation factor XII, anticorps coagulation factor XII (Hageman factor), anticorps F12

Sujet: Name/Gene ID: F12
Subfamily: Serine S1
Family: Protease

Synonyms: F12, Beta-factor XIIa part 2, Beta-factor XIIa part 1, Coagulation factor XII, F12 deficiency, Factor XII, Factor XII deficiency, HAE3, HAEX, Hageman factor, HAF

ID gène: 2161

UniProt: P00748

Pathways: Système du Complément