AKT2 anticorps

N° du produit ABIN965531

Il existe 3+ publications pour ce produit. L’anticorps anti-AKT2 Polyclonal Lapin est utilisé pour la détection de AKT2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IHC.

Aperçu rapide pour AKT2 anticorps (ABIN965531)

Antigène: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AKT2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-AKT2 anticorps

Specificité: Akt2 (Ab-474) antibody detects endogenous levels of total Akt2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human Akt2 around the phosphorylation site of serine 474 (Q-F-SP-Y-S).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-AKT2 (ABIN965531)

Sun, Paciga, Feldman, Yuan, Coppola, Lu, Shelley, Nicosia, Cheng: "Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K." dans: Cancer research, Vol. 61, Issue 16, pp. 5985-91, (2001) (PubMed).

Yuan, Sun, Feldman, Wang, Ma, Jiang, Coppola, Nicosia, Cheng: "Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer." dans: Oncogene, Vol. 19, Issue 19, pp. 2324-30, (2000) (PubMed).

Meier, Alessi, Cron, Andjelković, Hemmings: "Mitogenic activation, phosphorylation, and nuclear translocation of protein kinase Bbeta." dans: The Journal of biological chemistry, Vol. 272, Issue 48, pp. 30491-7, (1997) (PubMed).

Détails sur AKT2

Antigène: AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))

Autre désignation: AKT2

Pathways: Signalisation PI3K-Akt, Signalisation RTK, AMPK Signaling, Signalisation TLR, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Hepatitis C, VEGF Signaling