CIB1 anticorps

N° du produit ABIN965898

Détail du produit anti-CIB1 anticorps

Antigène: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CIB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of CIB1 expressed in E. Coli.

Clone: 5A1F5E12-5A1H7E12

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-CIB1 (ABIN965898)

White, Yang, Monteiro, Foskett: "CIB1, a ubiquitously expressed Ca2+-binding protein ligand of the InsP3 receptor Ca2+ release channel." dans: The Journal of biological chemistry, Vol. 281, Issue 30, pp. 20825-33, (2006) (PubMed).

Détails sur CIB1

Antigène: CIB1 (Calcium and Integrin-Binding Protein 1 (CIB1))

Autre désignation: CIB1 (CIB1 Produits)

Synonymes: anticorps zgc:112015, anticorps CIB, anticorps CIBP, anticorps KIP1, anticorps PRKDCIP, anticorps SIP2-28, anticorps Cibkip, anticorps Kip, anticorps Prkdcip, anticorps Cib, anticorps Sip2-28, anticorps calcium and integrin binding 1 (calmyrin), anticorps calcium and integrin-binding protein 1, anticorps calcium and integrin binding 1, anticorps Calcium and integrin-binding protein 1, anticorps cib1, anticorps CpipJ_CPIJ003501, anticorps CIB1, anticorps kip1, anticorps Cib1

Sujet: CIB1(also designated calcium and integrin binding 1 or calmyrin),with 191-amino acid protein(about 21kDa), belongs to the calcium-binding protein family.CIB1 is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end joining.CIB1 is an EF-hand-containing protein that binds multiple effector proteins, including the platelet alpha(IIb)beta(3) integrin and several serine/threonine kinases and potentially modulates their function.CIB1 regulates platelet aggregation in hemostasis through a specific interaction with the alpha(IIb) cytoplasmic domain of platelet integrin alpha(IIb)beta(3). CIB1 is also ubiquitously expressed activating and inhibiting protein ligand of the InsP3R.
Synonyms: CIB, KIP, KIP1, SIP228

ID gène: 10519