SLC31A2 anticorps (N-Term)

N° du produit ABIN965919

Détail du produit anti-SLC31A2 anticorps

Antigène: SLC31A2 (Solute Carrier Family 31 (Copper Transporters), Member 2 (SLC31A2))

Épitope: N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC31A2 est non-conjugé

Application: Immunohistochemistry (IHC)

Purification: Purified by antigen-specific affinity chromatography.

Immunogène: Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human COPT2(copper transporter 2)

Information d'application

Indications d'application: ELISA, Western blotting: 1µg/ml for 2hrs.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: This antibody is stored in PBS, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SLC31A2

Antigène: SLC31A2 (Solute Carrier Family 31 (Copper Transporters), Member 2 (SLC31A2))

Autre désignation: COPT2 (SLC31A2 Produits)

Synonymes: anticorps COPT2, anticorps CTR2, anticorps hCTR2, anticorps ctr2, anticorps xem1, anticorps copt2, anticorps SLC31A2, anticorps AI604396, anticorps copper transporter 2, anticorps solute carrier family 31 member 2, anticorps solute carrier family 31 member 2 S homeolog, anticorps solute carrier family 31, member 2, anticorps copper transporter 2, anticorps SLC31A2, anticorps slc31a2.S, anticorps slc31a2, anticorps Slc31a2, anticorps COPT2

Sujet: The COPT2(copper transporter 2) is involved in low-affinity copper uptake. COPT2 is a multi-pass membrane protein and belongs to the SLC31A transporter family. The redox active metal copper is an essential cofactor in critical biological processes such as respiration, iron transport,oxidative stress protection, hormone production, and pigmentation. A widely conserved family of high-affinity copper transport proteins (Ctr proteins) mediates copper uptake at the plasma membrane. A series of clustered methionine residues in the hydrophilic extracellular domain, and an MXXXM motif in the second transmembrane domain, are important for copper uptake. These methionine probably coordinate copper during the process of metal transport