CST3 anticorps (C-Term)

N° du produit ABIN965952

Détail du produit anti-CST3 anticorps

Antigène: CST3 (Cystatin C (CST3))

Épitope: AA 45-63, C-Term

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Polyclonal

Conjugué: Cet anticorp CST3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminal of human Cystatin C (45-63aa), identical to the related mouse and rat sequence.

Information d'application

Indications d'application: WB: The detection limit for Cystatin C is approximately 2.5ng/lane under non-reducing and reducing conditions.

Restrictions: For Research Use only

Stockage

Reconstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Stock: -20 °C

Détails sur CST3

Antigène: CST3 (Cystatin C (CST3))

Autre désignation: Cystatin C (CST3 Produits)

Synonymes: anticorps armd11, anticorps fb51d07, anticorps wu:fb24g06, anticorps wu:fb51d07, anticorps wu:fc55f03, anticorps zgc:136227, anticorps ARMD11, anticorps CysC, anticorps CYSC, anticorps cystatin C, anticorps cystatin C L homeolog, anticorps cystatin C (amyloid angiopathy and cerebral hemorrhage), anticorps cystatin 3, anticorps CST3, anticorps cst3.L, anticorps cst3, anticorps cystatin 3, anticorps Cst3

Sujet: Cystatin C or cystatin 3, a protein encoded by the CST3 gene, is mainly used as a biomarker of kidney function. Recently, it has been studied for its role in predicting new-onset or deteriorating cardiovascular disease. It also seems to play a role in brain disorders involving amyloid, such as Alzheimer's disease. By human-rodent somatic cell hybridizations, Abrahamson et al. (1989) mapped the human CST3 to chromosome 20. Cystatin C was originally described as a constituent of normal cerebrospinal fluid (CSF) and of urine from patients with renal failure (Grubb and Lofberg, 1982). It is present in a number of neuroendocrine cells and its concentration in the CSF was reported to be 5.5 times that in plasma of healthy adults (Lofberg and Grubb, 1979, Lofberg et al., 1981, Lofberg et al., 1983). Grubb and Lofberg detected the protein in human pituitary gland, and suggested that it is part of the gastroenteropancreatic neuroendocrine system.