EPHA1 anticorps

N° du produit ABIN966070

Détail du produit anti-EPHA1 anticorps

Antigène: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Reactivité: Humain

Hôte: Veuillez nous consulter SVP

Clonalité: Monoclonal

Conjugué: Cet anticorp EPHA1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Specificité: Ni-NTA purified truncated recombinant EphA1 expressed in E. Coli strain BL21 (DE3)

Purification: Antibodies are purified by protein A affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1: 200- 1: 1,000
IHC-P: 1: 200- 1: 1,000
IHC-F: 1: 200- 1: 1,000
ELISA: Propose dilution 1: 10,000.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Références pour anticorps anti-EPHA1 (ABIN966070)

Duffy, Steiner, Tam, Boyd: "Expression analysis of the Epha1 receptor tyrosine kinase and its high-affinity ligands Efna1 and Efna3 during early mouse development." dans: Gene expression patterns : GEP, Vol. 6, Issue 7, pp. 719-23, (2006) (PubMed).

Pasquale: "Eph receptor signalling casts a wide net on cell behaviour." dans: Nature reviews. Molecular cell biology, Vol. 6, Issue 6, pp. 462-75, (2005) (PubMed).

Détails sur EPHA1

Antigène: EPHA1 (Ephrin Type A Receptor 1 (EPHA1))

Autre désignation: EphA1 (EPHA1 Produits)

Synonymes: anticorps EPH, anticorps EPHT, anticorps EPHT1, anticorps 5730453L17Rik, anticorps AL033318, anticorps Eph, anticorps Esk, anticorps EPHA9, anticorps EPH receptor A1, anticorps Eph receptor A1, anticorps EPHA1, anticorps Epha1

Sujet: EPH receptor A1 (EphA1), with 976-amino acid protein(about 107 kDa), belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. The Eph subfamily represents the largest group of receptor protein tyrosine kinases identified to date and their ligands, the ephrins,can be subdivided into two major subclasses, ephrin-A and ephrin-B. Interaction of Eph receptor tyrosine kinases with their membrane bound ephrin ligands initiates bidirectional signaling events that regulate cell migratory and adhesive behavior, particularly in the nervous system. They have been implicated in various developmental processes, including axonal guidance, angiogenesis, morphogenesis and carcinogenesis.

ID gène: 2041