FAF1 anticorps (N-Term)

N° du produit ABIN966117

Détail du produit anti-FAF1 anticorps

Antigène: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAF1 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Souris, Rat (Rattus)

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for FAS-associated factor 1 ( FAF1) detection. Tested with WB in Human, Mouse, Rat.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminal of human FAF1, identical to the related mouse and rat sequences.< br/>Immunogen was affinity purified.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.

Références pour anticorps anti-FAF1 (ABIN966117)

Park, Jang, Lee, Lee, Kim: "Fas-associated factor-1 inhibits nuclear factor-kappaB (NF-kappaB) activity by interfering with nuclear translocation of the RelA (p65) subunit of NF-kappaB." dans: The Journal of biological chemistry, Vol. 279, Issue 4, pp. 2544-9, (2004) (PubMed).

Ryu, Chae, Lee, Kim: "Identification and characterization of human Fas associated factor 1, hFAF1." dans: Biochemical and biophysical research communications, Vol. 262, Issue 2, pp. 388-94, (1999) (PubMed).

Détails sur FAF1

Antigène: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Autre désignation: FAS-associated factor 1(hFAF1) (FAF1 Produits)

Synonymes: anticorps faf1, anticorps MGC53741, anticorps MGC80303, anticorps FAF1, anticorps zgc:55752, anticorps wu:fc25h12, anticorps HFAF1s, anticorps UBXD12, anticorps UBXN3A, anticorps hFAF1, anticorps AA408698, anticorps Dffrx, anticorps Fam, anticorps Fas (TNFRSF6) associated factor 1 S homeolog, anticorps Fas (TNFRSF6) associated factor 1 L homeolog, anticorps Fas associated factor 1, anticorps Fas (TNFRSF6) associated factor 1, anticorps Fas-associated factor 1, anticorps faf1.S, anticorps faf1.L, anticorps FAF1, anticorps faf1, anticorps Faf1

Sujet: Fas-associated factor-1 (FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i. e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2. 8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.

Pathways: Maintenance of Protein Location