FOXO1 anticorps

N° du produit ABIN966148

Cet anticorps Lapin Polyclonal détecte spécifiquement FOXO1 dans IHC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat. Il a été cité dans 2+ publications.

Aperçu rapide pour FOXO1 anticorps (ABIN966148)

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-FOXO1 anticorps

Specificité: FKHR (Ab-256) antibody detects endogenous levels of total FKHR protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human FKHR around the phosphorylation site of serine 256 (A-A-SP-M-D).

Information d'application

Indications d'application: WB: 1:500~1:1000
IHC: 1:50~1:100.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-FOXO1 (ABIN966148)

Gan, Zheng, Chabot, Unterman, Quirion: "Nuclear/cytoplasmic shuttling of the transcription factor FoxO1 is regulated by neurotrophic factors." dans: Journal of neurochemistry, Vol. 93, Issue 5, pp. 1209-19, (2005) (PubMed).

Smith, Norton, Gorospe, Jiang, Nemoto, Holbrook, Finkel, Kusiak: "Phosphorylation of p66Shc and forkhead proteins mediates Abeta toxicity." dans: The Journal of cell biology, Vol. 169, Issue 2, pp. 331-9, (2005) (PubMed).

Détails sur FOXO1

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Autre désignation: FKHR

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling