IGFBP2 anticorps (AA 180-328)

N° du produit ABIN966350

Détail du produit anti-IGFBP2 anticorps

Antigène: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Épitope: AA 180-328

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IGFBP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E. Coli.

Clone: 1F6F6

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-IGFBP2 (ABIN966350)

Stewart, Weigel: "Role of insulin-like growth factor binding proteins in 1alpha,25-dihydroxyvitamin D(3)-induced growth inhibition of human prostate cancer cells." dans: The Prostate, Vol. 64, Issue 1, pp. 9-19, (2005) (PubMed).

Fisher, Meyer, Garber, Dealy: "Role of IGFBP2, IGF-I and IGF-II in regulating long bone growth." dans: Bone, Vol. 37, Issue 6, pp. 741-50, (2005) (PubMed).

Miyake, Hara, Yamanaka, Muramaki, Gleave, Eto: "Introduction of insulin-like growth factor binding protein-2 gene into human bladder cancer cells enhances their metastatic potential." dans: Oncology reports, Vol. 13, Issue 2, pp. 341-5, (2005) (PubMed).

Détails sur IGFBP2

Antigène: IGFBP2 (Insulin-Like Growth Factor Binding Protein 2, 36kDa (IGFBP2))

Autre désignation: IGFBP2 (IGFBP2 Produits)

Synonymes: anticorps IBP2, anticorps IGF-BP53, anticorps AI255832, anticorps IBP-2, anticorps Igfbp-2, anticorps mIGFBP-2, anticorps IGFBP-2, anticorps ILGFBPA, anticorps pIGFBP-2, anticorps igfbp2, anticorps MGC65741, anticorps MGC76823, anticorps MGC174445, anticorps IGFBP2, anticorps ibp2, anticorps igf-bp53, anticorps igfbp2a, anticorps si:ch211-2k18.3, anticorps insulin like growth factor binding protein 2, anticorps insulin-like growth factor binding protein 2, anticorps insulin-like growth factor binding protein 2a, anticorps insulin-like growth factor binding protein 2b, anticorps IGFBP2, anticorps Igfbp2, anticorps igfbp2a, anticorps igfbp2, anticorps igfbp2b

Sujet: IGFBP2: insulin-like growth factor binding protein 2. IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
Synonyms: IBP2, IGF-BP53

ID gène: 3485

Pathways: Myometrial Relaxation and Contraction, Growth Factor Binding, Activated T Cell Proliferation