HSC70 Interacting Protein HIP anticorps

N° du produit ABIN967083

Détail du produit anti-HSC70 Interacting Protein HIP anticorps

Antigène: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Reactivité: Humain, Singe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HSC70 Interacting Protein HIP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ST13 expressed in E. Coli.

Clone: 3B10

Isotype: IgG1

Information d'application

Indications d'application: Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test.

Restrictions: For Research Use only

Stockage

Format: Liquid

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Références pour anticorps anti-HSC70 Interacting Protein HIP (ABIN967083)

Velten, Gomez-Vrielynck, Chaffotte, Ladjimi: "Domain structure of the HSC70 cochaperone, HIP." dans: The Journal of biological chemistry, Vol. 277, Issue 1, pp. 259-66, (2002) (PubMed).

Détails sur HSC70 Interacting Protein HIP

Antigène: HSC70 Interacting Protein HIP (ST13) (Suppression of Tumorigenicity 13 (ST13))

Autre désignation: ST13 (ST13 Produits)

Synonymes: anticorps CG32789, anticorps Dmel\\CG32789, anticorps anon-EST:fe1A9, anticorps 1110007I03Rik, anticorps 3110002K08Rik, anticorps AW555194, anticorps HIP, anticorps HOP, anticorps HSPABP, anticorps HSPABP1, anticorps PRO0786, anticorps SNC6, anticorps p48, anticorps AAG2, anticorps FAM10A1, anticorps FAM10A4, anticorps P48, anticorps Hsc/Hsp70-interacting protein, anticorps suppression of tumorigenicity 13, anticorps ST13, Hsp70 interacting protein, anticorps suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein), anticorps HIP, anticorps St13, anticorps ST13

Sujet: ST13 (suppression of tumorigenicity protein 13), also known as Hip (HSP70-interacting protein), is one of several cochaperones that regulate activities of the HSP70 chaperone family. The homo-oligomeric protein Hip cooperates with HSP70 in protein folding by stabilizing the ADP-bound state of HSP70. Hip directly binds to the ATPase domain of HSP70 when it is converted to the ADP-bound state by proteins of the HSP40 family. By collaborating with other positive co-factors such as HSP40 and Hop, or competing with negative co-factors such as Bag1, Hip may facilitate the chaperone function of HSP70 in protein folding and repair, and in controlling the activity of regulatory proteins such as steroid receptors and various regulators of proliferation or apoptosis.
Synonyms: HIP, HOP, P48, AAG2, SNC6, HSPABP, FAM10A1, FAM10A4, HSPABP1, ST13

Poids moléculaire: 48kDa

ID gène: 6767