FGFR1 anticorps (AA 22-376)
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- Antigène Voir toutes FGFR1 Anticorps
- FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
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Épitope
- AA 22-376
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp FGFR1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- purified
- Immunogène
- Purified recombinant extracellular fragment of human FGFR1 (aa22-376) fused with hIgGFc tag expressed in HEK293 cells.
- Clone
- 3D4F7
- Isotype
- IgG2b
- Top Product
- Discover our top product FGFR1 Anticorps primaire
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- Indications d'application
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- 4°C, -20°C for long term storage
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FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis." dans: Breast cancer research : BCR, Vol. 9, Issue 2, pp. R23, (2007) (PubMed).
: "Fibroblast growth factor receptor-1 expression is required for hematopoietic but not endothelial cell development." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 25, Issue 5, pp. 944-9, (2005) (PubMed).
: "90-kDa ribosomal S6 kinase is a direct target for the nuclear fibroblast growth factor receptor 1 (FGFR1): role in FGFR1 signaling." dans: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29325-35, (2004) (PubMed).
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FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis." dans: Breast cancer research : BCR, Vol. 9, Issue 2, pp. R23, (2007) (PubMed).
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- Antigène
- FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))
- Autre désignation
- FGFR1 (FGFR1 Produits)
- Synonymes
- anticorps FGFR, anticorps fgfr, anticorps X1FGFR, anticorps XFGFR-1, anticorps XFGFRA2, anticorps bfgfr, anticorps cek, anticorps fgfr1, anticorps flg, anticorps flt-2, anticorps flt2, anticorps kal2, anticorps ogd, anticorps xfgfr1, anticorps CG7223, anticorps CT22273, anticorps CT39172, anticorps DFGF-R1, anticorps DFGF-R2, anticorps DFR-1, anticorps DFR1, anticorps DFR1/DFGF-R2, anticorps DPR3, anticorps DTRK(FR1), anticorps Dfr-1, anticorps Dfr1, anticorps DmHD-38, anticorps Dmel\\CG7223, anticorps Dtk1, anticorps EMS2, anticorps FGF-R2, anticorps FGFR2, anticorps FR1, anticorps Fr1, anticorps HD-38, anticorps HTL/FGFR1, anticorps Htl, anticorps Tk1, anticorps dtk1, anticorps i100, anticorps i150, anticorps i79, anticorps j372, anticorps cd331, anticorps fgfbr, anticorps fgfr-1, anticorps hbgfr, anticorps n-sam, anticorps ach, anticorps cd333, anticorps cek2, anticorps fgfr-3, anticorps hsfgfr3ex, anticorps jtk4, anticorps BFGFR, anticorps CD331, anticorps CEK, anticorps FGFBR, anticorps FGFR-1, anticorps FLG, anticorps FLT-2, anticorps FLT2, anticorps HBGFR, anticorps HH2, anticorps KAL2, anticorps N-SAM, anticorps OGD, anticorps bFGF-R-1, anticorps AW208770, anticorps Eask, anticorps Fgfr-1, anticorps Flt-2, anticorps Hspy, anticorps FLG-1, anticorps FGFRI, anticorps x1fgfr, anticorps cb231, anticorps sb:cb231, anticorps fibroblast growth factor receptor, anticorps fibroblast growth factor receptor 1 S homeolog, anticorps basic fibroblast growth factor receptor 1, anticorps heartless, anticorps fibroblast growth factor receptor 1, anticorps fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) L homeolog, anticorps Fibroblast growth factor receptor 1, anticorps fibroblast growth factor receptor 1 L homeolog, anticorps fibroblast growth factor receptor 1a, anticorps FGFR, anticorps fgfr, anticorps fgfr1.S, anticorps CpipJ_CPIJ005849, anticorps htl, anticorps fgfr1, anticorps fgfr3.L, anticorps FGFR1, anticorps Fgfr1, anticorps fgfr1.L, anticorps fgfr1a
- Sujet
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Description: Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome, and CD331, is a receptor tyrosine kinase whose ligands are specific members of the fibroblast growth factor family. FGFR1 has been shown to be associated with Pfeiffer syndrome. It is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
Aliases: CEK, FLG, OGD, FLT2, KAL2, BFGFR, CD331, FGFBR, HBGFR
- Poids moléculaire
- 92 kDa
- ID gène
- 2260
- HGNC
- 2260
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteins
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