FYN anticorps

N° du produit ABIN969159

Détail du produit anti-FYN anticorps

Antigène: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FYN est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purification: purified

Immunogène: Purified recombinant fragment of human FYN expressed in E. coli.

Clone: 2A10

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: 4°C, -20°C for long term storage

Références pour anticorps anti-FYN (ABIN969159)

Brignatz, Paronetto, Opi, Cappellari, Audebert, Feuillet, Bismuth, Roche, Arold, Sette, Collette: "Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn." dans: Molecular and cellular biology, Vol. 29, Issue 24, pp. 6438-48, (2009) (PubMed).

Lu, Zhu, Cvrljevic, Huang, Sarkaria, Ahkavan, Dang, Dinca, Plaisier, Oderberg, Lee, Chen, Caldwell, Xie, Loo, Seligson, Chakravari, Lee, Weinmann, Cloughesy, Nelson, Bergers, Graeber, Furnari, James, Cavenee, Johns, Mischel: "Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients." dans: Cancer research, Vol. 69, Issue 17, pp. 6889-98, (2009) (PubMed).

Kitkumthorn, Yanatatsanajit, Kiatpongsan, Phokaew, Triratanachat, Trivijitsilp, Termrungruanglert, Tresukosol, Niruthisard, Mutirangura: "Cyclin A1 promoter hypermethylation in human papillomavirus-associated cervical cancer." dans: BMC cancer, Vol. 6, pp. 55, (2006) (PubMed).

Détails sur FYN

Antigène: FYN (FYN Oncogene Related To SRC, FGR, YES (FYN))

Autre désignation: FYN (FYN Produits)

Synonymes: anticorps im:6908851, anticorps si:dkey-119m7.5, anticorps zgc:109996, anticorps c-fyn, anticorps cfyn-a, anticorps SLK, anticorps SYN, anticorps p59-FYN, anticorps PKC, anticorps fyn, anticorps zgc:86720, anticorps AI448320, anticorps AW552119, anticorps FYN proto-oncogene, Src family tyrosine kinase, anticorps FYN proto-oncogene, Src family tyrosine kinase S homeolog, anticorps FYN proto-oncogene, Src family tyrosine kinase b, anticorps FYN proto-oncogene, Src family tyrosine kinase L homeolog, anticorps FYN proto-oncogene, Src family tyrosine kinase a, anticorps Fyn proto-oncogene, anticorps FYN, anticorps fyn.S, anticorps fynb, anticorps fyn.L, anticorps Fyn, anticorps fyna

Sujet:

Description: This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist.

Aliases: SLK, SYN, MGC45350

Poids moléculaire: 61 kDa

ID gène: 2534

HGNC: 2534

Pathways: Signalistation JAK/STAT, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Feeding Behaviour, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Activated T Cell Proliferation, Thromboxane A2 Receptor Signaling