JAK2 anticorps (AA 745-955)

N° du produit ABIN969223

Cet anticorps Souris Monoclonal détecte spécifiquement JAK2 dans WB et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour JAK2 anticorps (AA 745-955) (ABIN969223)

Antigène: JAK2 (Janus Kinase 2 (JAK2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp JAK2 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1C1

Détail du produit anti-JAK2 anticorps

Épitope: AA 745-955

Fonction: JAK2 Antibody

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of JAK2(745-955aa) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: ELISA: 1/10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-JAK2 (ABIN969223)

Hermanns, Radtke, Haan, Schmitz-Van de Leur, Tavernier, Heinrich, Behrmann: "Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 12, pp. 6651-8, (2000) (PubMed).

Détails sur JAK2

Antigène: JAK2 (Janus Kinase 2 (JAK2))

Autre désignation: JAK2

Sujet: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Poids moléculaire: 130.6 kDa

ID gène: 3717

UniProt: O60674

Pathways: Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response