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JAK2 anticorps (AA 745-955)

Name: JAK2 anticorps (AA 745-955)
Brand: antibodies-online
SKU: ABIN969223
Price: 592.94 EUR
Availability: InStock

JAK2 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal 1C1 unconjugated

Western blot analysis using JAK2 mouse mAb against THP-1(1) cell lysate.

1 image

(1 reference)

N° du produit ABIN969223

Fiche de données

Antigène Voir toutes JAK2 Anticorps

JAK2 (Janus Kinase 2 (JAK2))
Épitope
37

34

16

16

12

10

8

7

6

6

6

6

6

5

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 745-955
Reactivité
171

101

97

18

18

3

2

2

1
Humain
Hôte
174

5

2
Souris
Anticorps secondaires appropriés
Clonalité
159

22
Monoclonal
Conjugué
91

15

9

6

6

6

6

6

6

6

5

3

3

3

3

3

3

1
Cet anticorp JAK2 est non-conjugé
Application
129

80

62

57

29

27

25

22

17

12

10

5

4

2

1

1

1
Western Blotting (WB), ELISA

Purification

purified

Immunogène

Purified recombinant fragment of JAK2(745-955aa) expressed in E. coli.

Clone

1C1

Isotype

IgG1

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Indications d'application

ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions

For Research Use only
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C/-20 °C

Stockage commentaire

4°C, -20°C for long term storage
Hermanns, Radtke, Haan, Schmitz-Van de Leur, Tavernier, Heinrich, Behrmann: "Contributions of leukemia inhibitory factor receptor and oncostatin M receptor to signal transduction in heterodimeric complexes with glycoprotein 130." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 12, pp. 6651-8, (2000) (PubMed).
Antigène

JAK2 (Janus Kinase 2 (JAK2))

Autre désignation

JAK2 (JAK2 Produits)

Synonymes

anticorps JAK2bCA, anticorps jak2, anticorps JTK10, anticorps THCYT3, anticorps AI504024, anticorps C81284, anticorps Fd17, anticorps JAK-2, anticorps Janus kinase 2b, anticorps Janus kinase 2, anticorps jak2b, anticorps JAK2, anticorps Jak2

Sujet

Description: This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Aliases: JTK10, JAK2

Poids moléculaire

130.6 kDa

ID gène

3717

HGNC

3717

Pathways

Signalistation JAK/STAT, Signalisation RTK, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response