FOXO1 anticorps

N° du produit ABIN969521

2+ publications sont disponibles pour ce produit. L’anticorps anti-FOXO1 Monoclonal produit chez le Souris a été validé pour WB, IHC, ELISA et ICC. Il convient pour la détection de FOXO1 dans des échantillons provenant de Humain et Souris. }

Aperçu rapide pour FOXO1 anticorps (ABIN969521)

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FOXO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Clone: 3B6

Détail du produit anti-FOXO1 anticorps

Fonction: FOXO1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human FOXO1 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Références pour anticorps anti-FOXO1 (ABIN969521)

Lau, Koty, Nalbantoglu: "Differential response of glioma cells to FOXO1-directed therapy." dans: Cancer research, Vol. 69, Issue 13, pp. 5433-40, (2009) (PubMed).

Srivastava, Yasruel, Nalbantoglu: "Impaired medulloblastoma cell survival following activation of the FOXO1 transcription factor." dans: International journal of oncology, Vol. 35, Issue 5, pp. 1045-51, (2009) (PubMed).

Détails sur FOXO1

Antigène: FOXO1 (Forkhead Box O1 (FOXO1))

Autre désignation: FOXO1

Sujet: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Poids moléculaire: 69.7 kDa

UniProt: Q12778

Pathways: Signalisation PI3K-Akt, Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling