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Bacteria Polyclonal MAP1LC3B Primary Antibody pour ELISA, ICC - ABIN250638
Sarkar, Krishna, Imarisio, Saiki, OKane, Rubinsztein: A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. dans Human molecular genetics 2008
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Cow (Bovine) Polyclonal MAP1LC3B Primary Antibody pour EM, FACS - ABIN153145
Pyo, Nah, Kim, Lee, Heo, Lee, Jung: Compensatory activation of ERK1/2 in Atg5-deficient mouse embryo fibroblasts suppresses oxidative stress-induced cell death. dans Autophagy 2008
Show all 206 Pubmed References
Human Polyclonal MAP1LC3B Primary Antibody pour ICC, IF - ABIN388484
English, Chemali, Duron, Rondeau, Laplante, Gingras, Alexander, Leib, Norbury, Lippé, Desjardins: Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. dans Nature immunology 2009
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Bacteria Polyclonal MAP1LC3B Primary Antibody pour ELISA, IHC (fro) - ABIN250640
Mizushima, Yamamoto, Hatano, Kobayashi, Kabeya, Suzuki, Tokuhisa, Ohsumi, Yoshimori: Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. dans The Journal of cell biology 2001
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Polyclonal MAP1LC3B Primary Antibody pour IHC (fro), WB - ABIN540679
Miller, Zhao, Stephenson, Cadwell, Pua, Lee, Mizushima, Iwasaki, He, Swat, Virgin: The autophagy gene ATG5 plays an essential role in B lymphocyte development. dans Autophagy 2008
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Cow (Bovine) Polyclonal MAP1LC3B Primary Antibody pour ICC, IF - ABIN269556
Aoki, Takada, Kondo, Sawaya, Aggarwal, Kondo: Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways. dans Molecular pharmacology 2007
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Bacteria Polyclonal MAP1LC3B Primary Antibody pour ELISA, ICC - ABIN250639
Settembre, Fraldi, Jahreiss, Spampanato, Venturi, Medina, de Pablo, Tacchetti, Rubinsztein, Ballabio: A block of autophagy in lysosomal storage disorders. dans Human molecular genetics 2007
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Human Monoclonal MAP1LC3B Primary Antibody pour FACS, ELISA - ABIN969267
Othman, Kaur, Mutee, Muhammad, Tan: Immunohistochemical expression of MAP1LC3A and MAP1LC3B protein in breast carcinoma tissues. dans Journal of clinical laboratory analysis 2009
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Human Polyclonal MAP1LC3B Primary Antibody pour WB - ABIN1883178
Han, Hou, Goldstein, Lu, Stolz, Yin, Rabinowich: Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. dans The Journal of biological chemistry 2008
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Bacteria Polyclonal MAP1LC3B Primary Antibody pour ELISA, ICC - ABIN406993
Matta, Kumar: AKT mediated glycolytic shift regulates autophagy in classically activated macrophages. dans The international journal of biochemistry & cell biology 2015
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Here the authors present evidence for phosphorylation-driven regulation of the Nix:LC3B interaction. Isothermal titration calorimetry and NMR indicate a ~100 fold enhanced affinity of the serine 34/35-phosphorylated Nix (Montrer BNIP3L Anticorps) LC3 (Montrer MAP1LC3A Anticorps)-interacting region (LIR (Montrer CD300C Anticorps)) to LC3B and formation of a very rigid complex compared to the non-phosphorylated sequence.
The results suggest that autophagy-associated proteins LC3A (Montrer MAP1LC3A Anticorps), LC3B, and Beclin-1 (Montrer BECN1 Anticorps) might be potential biomarkers for subclassification, differentiation, and local metastasis in primary lung tumor.
FYCO1 (Montrer FYCO1 Anticorps) regulates accumulation of post-mitotic midbodies by mediating LC3 (Montrer MAP1LC3A Anticorps)-dependent midbody degradation
Simultaneous high expression of LC3B (and ULK1 (Montrer ULK1 Anticorps)) had a poorer survival rate in hepatocellular carcinoma patients.
LC3B and ESRRA (Montrer ESRRA Anticorps) might be a useful prognostic factor in patients with Muscle-invasive bladder cancer. The co-expression of LC3B and ESRRA (Montrer ESRRA Anticorps) might be a prognostic and therapeutic target for patients with bladder cancer.
High levels of LC3B is associated with non-small cell lung cancer.
LC3b was significantly overexpressed in malignant compared to benign prostate tissue. However, positive LC3b immunoreactivity in PCa (Montrer FLVCR1 Anticorps), as a marker of increased autophagy, was independently associated with a reduced disease-specific mortality.
Our results suggested that activated Akt (Montrer AKT1 Anticorps)/mTOR (Montrer FRAP1 Anticorps)-autophagy may have a role in the local T cell-mediated immunoregulatory mechanism of oral lichen planus (OLP). LC3B might be a valuable marker to monitor the disease severity of OLP.
presence of LC3B puncta and HMGB1 (Montrer HMGB1 Anticorps) expression in malignant cells correlate with the immune infiltrate in breast cancer
the L341V mutation limits the critical step of SQSTM1 (Montrer SQSTM1 Anticorps) recruitment to the phagophore
At the microtubule-actin crossover junction, ATG4B (Montrer ATG4B Anticorps) detaches LC3B from melanosomal membranes by enzymatic delipidation.
Data show that interaction between miR (Montrer MLXIP Anticorps)-471-5p and autophagy member proteins regulates clearance of apoptotic germ cells via LC3 (Montrer MAP1LC3A Anticorps)-associated phagocytosis (LAP).
The crystal structure of mouse LC3B in complex with the FYCO1 (Montrer FYCO1 Anticorps) LC3 (Montrer MAP1LC3A Anticorps)-interacting region (LIR (Montrer CD300C Anticorps)) reveals the importance of the flanking region of the LIR (Montrer CD300C Anticorps) motif.
Data suggest that maternal nutrition modulates expression of autophagy proteins p62/Sqstm1 (Montrer SQSTM1 Anticorps) and Lc3 (Montrer MAP1LC3A Anticorps)-II/Map1lc3 in liver and hypothalamus of offspring (newborn, suckling, and adult stages); for example, high-fat diet leading to maternal obesity up-regulates p62 (Montrer GTF2H1 Anticorps) and down-regulates Lc3 (Montrer MAP1LC3A Anticorps)-II in neonatal liver. (p62/Sqstm1 (Montrer SQSTM1 Anticorps) = sequestosome 1 (Montrer SQSTM1 Anticorps); Lc3 (Montrer MAP1LC3A Anticorps)-II/Map1lc3 = microtubule-associated protein (Montrer SPAG5 Anticorps) 1-light chain 3)
Treatment of aged mice and their derived macrophages with methyltransferase inhibitor (2)-epigallocatechin-3-gallate (EGCG) or specific DNA methyltransferase 2 (DNMT2 (Montrer TRDMT1 Anticorps)) siRNA restored the expression of Atg5 (Montrer ATG5 Anticorps) and LC3 (Montrer MAP1LC3A Anticorps) in vivo and in vitro.
MREG (Montrer MREG Anticorps)-dependent processing links both autophagic and phagocytic processes in LC3 (Montrer MAP1LC3A Anticorps)-associated phagocytosis. MREG (Montrer MREG Anticorps) participates in coordinating the association of phagosomes with LC3 (Montrer MAP1LC3A Anticorps) for content degradation with the MREG (Montrer MREG Anticorps) loss leading to phagosome accumulation.
This work identifies a previously unrecognized role for alphav and the autophagy components LC3 and atg5 in regulating TLR signalling and B-cell immunity.
Deficiency of autophagy protein Map1 (Montrer MOAP1 Anticorps)-LC3b mediates IL-17 (Montrer IL17A Anticorps)-dependent lung pathology during respiratory viral infection via ER stress-associated IL-1 (Montrer IL1A Anticorps).
This study suggests that autophagy could play a role in placental invasion system and that nutrient starvation affects LC3B expression.
Data indicate that the recombinant plasmid encoding pCMV-LC3 (Montrer MAP1LC3A Anticorps)-LpqH could be a practical strategy for the development of improved vaccines against Mycobacterium tuberculosis.
Data indicate that the expression of MAP1LC3A (Montrer MAP1LC3A Anticorps), B and autophagy-associated genes (ATG5 (Montrer ATG5 Anticorps), mTOR (Montrer FRAP1 Anticorps), Beclin-1 (Montrer BECN1 Anticorps)) was increased in normal pigs, while decreased in miniature pigs.
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in autophagy, a process that involves the bulk degradation of cytoplasmic component.
MAP1 light chain 3-like protein 2
, MAP1A/MAP1B LC3 B
, MAP1A/MAP1B light chain 3 B
, autophagy-related ubiquitin-like modifier LC3 B
, microtubule-associated proteins 1A/1B light chain 3B
, MAP1A/1B light chain 3 B
, autophagy-related protein LC3 B
, microtubule-associated proteins 1A/1B light chain 3
, microtubule-associated protein 1 light chain 3 beta