ROCK1 Protéines

Profil protéine

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.

Alternative names and synonyms associated with ROCK1

• Rho associated coiled-coil containing protein kinase 1 (ROCK1) anticorps
• Rho kinase (Rok) anticorps
• Rho-associated coiled-coil containing protein kinase 1 (Rock1) anticorps
• Rho-associated, coiled-coil containing protein kinase 1 (rock1) anticorps

• 1110055K06Rik anticorps
• CG9774 anticorps
• Dmel\\CG9774 anticorps
• DRhk anticorps
• drok anticorps
• Afficher tous les alias de synonymes
• LOC100229794 anticorps
• p160ROCK anticorps
• Rhk anticorps
• RhoK anticorps
• Rock anticorps
• ROCK-1 anticorps
• ROCK-I anticorps
• ROCK1 anticorps
• Rok anticorps
• ROKalpha/beta anticorps

Protein level used designations for ROCK1

Rho-associated coiled coil containing protein kinase 1 , rho-associated protein kinase 1 , Rho-associated, coiled-coil containing protein kinase 1 , CG9774-PA , DRho-kinase , ROCK , Rho-associated kinase , RhoA kinase , drosophila rho-associated kinase , rho kinase , rok-PA , Rho-associated coiled-coil forming kinase 1 , p160 ROCK-1 , p160ROCK , rho-associated, coiled-coil-containing protein kinase 1 , rho-associated, coiled-coil-containing protein kinase I , Rho-associated kinase beta , liver regeneration-related protein LRRG199 , p150 RhoA-binding kinase ROK beta , Rho kinase , p160-ROCK , renal carcinoma antigen NY-REN-35 , HEBM1 , cAMP-dependent protein kinase ROCK-I , cePKA , corneal epithelial Rho-associated-Ser/Thr kinase 1 , Rho-kinase beta , Rho-associated protein kinase 1 , rho-associated coiled-coil domain-containing protein kinase 1