Aperçu des produits pour anti-ADCY1 (ADCY1) Anticorps

Mouse (Murine) Adenylate Cyclase 1 (Brain) (ADCY1) interaction partners

1. data indicate that ST034307 is a selective small-molecule inhibitor of AC1 (Montrer HRASLS Anticorps) and suggest that selective AC1 (Montrer HRASLS Anticorps) inhibitors may be useful for managing pain.

2. Genetic deletion of AC8 (adenylyl cyclase 8 (Montrer ADCY8 Anticorps)) but not AC1 (Montrer HRASLS Anticorps) abolished long-lasting anxiety.

3. Following ethanol administration, phosphorylation of TrkB (Montrer NTRK2 Anticorps) is significantly increased in the striatum of Adcyl1 and Adcyl6 knock-out mice.

4. Findings provide evidence to link activation of alpha7 nAChRs to a cAMP rise via AC1 (Montrer HRASLS Anticorps), which defines a new signaling pathway employed by alpha7 nAChRs

5. Results indicate that thalamic AC1 (Montrer HRASLS Anticorps) plays a major role in patterning and refinement of the mouse thalamocortical circuitry

6. Adenylyl cyclase-mediated effects contribute to increased isoprenaline-induced cardiac contractility in TRPM4 (Montrer TRPM4 Anticorps)-deficient mice.

7. Results demonstrate that ADCY1 has an evolutionarily conserved role in hearing.

8. Data indicate that genetic ablation of RGS6 (Montrer RGS6 Anticorps) expression resulted in anxiolytic and antidepressant behavior by enhancing signaling through the 5-HT1A receptor (Montrer CC2D1A Anticorps)-adenylyl cyclase (AC) axis.

9. Contrast sensitivity is similarly reduced in Adcy1-/- mice.

10. These results suggest that AC1 (Montrer HRASLS Anticorps) in retinal ganglion cell axons mediates the development of retinotopy and eye-specific segregation in the superior colliculus and dorsal lateral geniculate nucleus.

Human Adenylate Cyclase 1 (Brain) (ADCY1) interaction partners

1. data indicate that ST034307 is a selective small-molecule inhibitor of AC1 and suggest that selective AC1 inhibitors may be useful for managing pain.

2. STC1 (Montrer STC1 Anticorps) interferes with CALCRL (Montrer CALCRL Anticorps) signaling during osteoblastogenesis via adenylate cyclase inhibition.

3. AC1 catalytic activity can be adjusted by mediating calmodulin activation of AC1 by reversible methionine oxidation in calmodulin.

4. Increased expression of AC1 in the forebrain leads to deficits in behavioral inhibition.

5. Results demonstrate that ADCY1 has an evolutionarily conserved role in hearing.

6. AGS3 (Montrer GPSM1 Anticorps) reduced D(2L)DR-mediated sensitization of AC1 and AC2.

7. Compartmentalized AC1-CFTR (Montrer CFTR Anticorps) association is responsible for Ca(2 (Montrer CA2 Anticorps)+)/cAMP cross-talk.

8. Tissue transglutaminase directly regulates adenylyl cyclase resulting in enhanced cAMP-response element-binding protein (CREB) activation.

9. Transgenic mice overexpressing type-1 adenylyl cyclase in the forebrain show elevated long-term potentiation (LTP (Montrer SCP2 Anticorps)), increased memory for object recognition and slower rates of extinction for contextual memory.

10. Expression of sensitization of AC1 involves Galpha (Montrer SUCLG1 Anticorps)(s)-adenylyl cyclase interactions.