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IKKi/IKKe Produits

(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase epsilon (IKBKE))

Catégories

IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).[supplied by OMIM, Oct 2009].

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Catégories IKKi/IKKe en vedette

IKKi/IKKe Anticorps

High quality antibodies with extensive validation data.

IKKi/IKKe Kits ELISA

Reliable ELISA kits for a wide range of species.

IKKi/IKKe Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

IKKi/IKKe recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN7254825
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (2)
  • (4)
N° du produit ABIN3020771
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN392751
Quantité 400 μL
Fiche technique Fiche technique

IKKi/IKKe recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6967599
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951456
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1138007
Quantité 96 tests
Fiche technique Fiche technique

IKKi/IKKe recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5569723
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5569722
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN2752825
Quantité 2 μg
Fiche technique Fiche technique

Dernières publications sur nos produits IKKi/IKKe

DeDiego, Nogales, Martinez-Sobrido, Topham: "Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication." dans: mBio, Vol. 10, Issue 4, (2020) (PubMed).

He, Ma, Tian, Wei, Zhu, Li, Zhang, Wang, Zhang, Zhong: "ERRα negatively regulates type I interferon induction by inhibiting TBK1-IRF3 interaction." dans: PLoS pathogens, Vol. 13, Issue 6, pp. e1006347, (2017) (PubMed).

Gao, Yang, Yuan, Huang, Xu, Mao, Yuan, Bi: "TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration." dans: Oncogenesis, Vol. 6, Issue 9, pp. e383, (2017) (PubMed).

Bharaj, Wang, Dawes, Yun, Park, Yen, Basler, Freiberg, Lee, Rajsbaum: "The Matrix Protein of Nipah Virus Targets the E3-Ubiquitin Ligase TRIM6 to Inhibit the IKKε Kinase-Mediated Type-I IFN Antiviral Response." dans: PLoS pathogens, Vol. 12, Issue 9, pp. e1005880, (2016) (PubMed).

Rajsbaum, Versteeg, Schmid, Maestre, Belicha-Villanueva, Martínez-Romero, Patel, Morrison, Pisanelli, Miorin, Laurent-Rolle, Moulton, Stein, Fernandez-Sesma, tenOever, García-Sastre: "Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKε kinase-mediated antiviral response." dans: Immunity, Vol. 40, Issue 6, pp. 880-95, (2014) (PubMed).

Sun, Sammut, Wang, Kurihara, Windle, Roodman, Galson: "TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 29, Issue 1, pp. 90-102, (2013) (PubMed).

Boehm, Zhao, Yao, Kim, Firestein, Dunn, Sjostrom, Garraway, Weremowicz, Richardson, Greulich, Stewart, Mulvey, Shen, Ambrogio, Hirozane-Kishikawa, Hill, Vidal, Meyerson, Grenier, Hinkle, Root et al.: "Integrative genomic approaches identify IKBKE as a breast cancer oncogene. ..." dans: Cell, Vol. 129, Issue 6, pp. 1065-79, (2007) (PubMed).

Luttjeboer, Harada, Hughes, Johnson, Lilford, Mol: "Tubal flushing for subfertility." dans: Cochrane database of systematic reviews (Online), Issue 3, pp. CD003718, (2007) (PubMed).

Sweeney, Mo, Firestein: "Antiviral gene expression in rheumatoid arthritis: role of IKKepsilon and interferon regulatory factor 3." dans: Arthritis and rheumatism, Vol. 56, Issue 3, pp. 743-52, (2007) (PubMed).

Aksoy, Albarani, Nguyen, Laes, Ruelle, De Wit, Willems, Goldman, Goriely: "Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells." dans: Blood, Vol. 109, Issue 7, pp. 2887-93, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à IKKi/IKKe

inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (IKBKE), inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon (ikbke), inhibitor of nuclear factor kappa B kinase subunit epsilon (IKBKE), inhibitor of nuclear factor kappa B kinase subunit epsilon L homeolog (ikbke.L), inhibitor of nuclear factor kappa B kinase subunit epsilon (ikbke), inhibitor of nuclear factor kappa B kinase subunit epsilon (Ikbke), inhibitor of kappaB kinase epsilon (Ikbke), AW558201, IKBKE, IKK-E, IKK-i, IKKE, IKKepsilon, IKKI, Ikki, MGC130907, zgc:100844

Protein level used designations for IKKi/IKKe

  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
  • IKKe
  • inhibitor of nuclear factor kappa-B kinase subunit epsilon
  • inhibitor of nuclear factor kappa-B kinase subunit epsilon-like
  • I-kappa-B kinase epsilon
  • IKK-epsilon
  • IKK-related kinase epsilon
  • inducible I kappa-B kinase
  • inducible IkappaB kinase
  • inhibitor of kappaB kinase epsilon
  • IKK-E
  • inducible IKappaB kinase
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