Détails pour le produit réf. ABIN3219439
Inhibition Assay (InhA), Functional Studies (Func)
Fonction 2-NP increased the duration of STAT1 tyrosine phosphorylation in response to IFN-gamma, and this may underlie its enhancement of STAT1-dependent transcription. Reflecting the fact that STAT1 can exert tumor-suppressive effects, 2-NP enhanced the ability of IFN-gamma to inhibit the proliferation of human breast cancer and fibrosarcoma cells.
Attributs du produit Tradename: AC1O9ODE, CTK5C2325
Target: STAT activator
Receptor: STAT1
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 97 % +
Formula C14H10N2O
Solubility DMSO > 10 mM
Sujet JAK/STAT Signaling
Poids moléculaire 222.24 g/mol
Numéro CAS 65182-56-1
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months