Apremilast (CC-10004)

Détails pour le produit réf. ABIN3220101
Inhibition Assay (InhA), Functional Studies (Func)
Fonction Apremilast (CC-10004) is a potent and orally active PDE4 and TNF-α inhibitor with IC50 of 74 nM and 77 nM, respectively.
Attributs du produit Target: PDE inhibitor
Receptor: PDE4, TNF-α
Status: INN,USAN
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 98.30 %
Formula C22H24N2O7S
Solubility 10 mM in DMSO
Sujet Metabolism
Poids moléculaire 460.50 g/mol
Numéro CAS 608141-41-9
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months