AT13148

Détails pour le produit réf. ABIN3220128
Application
Inhibition Assay (InhA), Functional Studies (Func)
Options
Fonction AT13148 is an oral, ATP-competitive, multi-AGC kinase inhibitor with IC50 of 38 nM/402 nM/50 nM, 8 nM, 3 nM, and 6 nM/4 nM for Akt1/2/3, p70S6K, PKA, and ROCKI/II, respectively. Phase 1.
Attributs du produit Target: Akt inhibitor, ROCK inhibitor,S6 Kinase inhibitor, PKA inhibitor
Receptor: PKA,ROCK2,ROCK1,p70S6K,Akt1,Akt3,SGK3,RSK1,Akt2
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 97 % +
Formula C17H16ClN3O
Solubility 200 mM in DMSO
Sujet PI3K/Akt/mTOR Signaling
Poids moléculaire 313.78 g/mol
Numéro CAS 1056901-62-2
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months