AZD9291

Détails pour le produit réf. ABIN3220169
Application
Inhibition Assay (InhA), Functional Studies (Func)
Options
Fonction AZD9291 is an oral, irreversible, and mutant-selective EGFR inhibitor with IC50 of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR in LoVo cells, respectively. Phase 3.
Attributs du produit Target: EGFR inhibitor
Receptor: EGFR
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 97 % +
Formula C28H33N7O2
Solubility 100 mM in DMSO
Sujet Tyrosine Kinase/Adaptors
Poids moléculaire 499.61 g/mol
Numéro CAS 1421373-65-0
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months