CAL-101 (Idelalisib, GS-1101)

Détails pour le produit réf. ABIN3220302
Application
Inhibition Assay (InhA), Functional Studies (Func)
Options
Fonction CAL-101 (Idelalisib, GS-1101) is a selective p110δ inhibitor with IC50 of 2.5 nM, shown to have 40- to 300-fold greater selectivity for p110δ than p110α/β/γ, and 400- to 4000-fold more selectivity to p110δ than C2β, hVPS34, DNA-PK and mTOR.
Attributs du produit Target: PI3K inhibitor, mTOR inhibitor
Receptor: PI3Kα/β/δ/γ, mTOR
Purification All the products are sent with COA, HPLC and NMR inspection report to guarantee the quality.
Pureté 98 %
Formula C22H18FN7O
Solubility DMSO ≥80mg/mL
Sujet PI3K/Akt/mTOR Signaling
Poids moléculaire 415.42 g/mol
Numéro CAS 870281-82-6
Indications d'application Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Solid
Stock -20 °C
Stockage commentaire For the majority of compounds, they could be dissolved in DMSO or other organic solvent.
Their stock solution can be stored at -20°C for up to 3 months and aliquoted for sampling convenience.
Several freeze/thaw cycles should not damage the activity of our small molecule products.
However, in many instances the aqueous solutions of some compounds need to be made fresh and cannot be stored. For these compounds, their solution should be prepared just before use and stored no longer than 24 hours.
Date de péremption 24 months