TNFRSF18 Kit ELISA

N° du produit ABIN2042695

Détail du produit TNFRSF18 Kit ELISA

Antigène: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Reactivité: Humain

Méthode de détection: Colorimetric

Type de méthode: Sandwich ELISA

Gamme de detection: 62.5-4000 pg/mL

Seuil minimal de détection: 62.5 pg/mL

Application: ELISA

Marque: BioAssay™

Réactivité croisée (Details): There is no detectable cross-reactivity with other relevant proteins.

Sensibilité: < 10 pg/mL

Ingrédients: 96-well plate pre-coated with anti-TNFRSF18/GITR, Human
Lyophilized recombinant TNFRSF18/GITR, Human standard, 10 ng/tube, 2Ea
Avidin-Biotin-Peroxidase Complex (ABC), 130 µL (1:100 dilution)
Sample diluent buffer, 30 mL
Antibody diluent buffer, 10 mL
ABC diluent buffer, 10 mL
TMB color developing agent, 10 mL
TMB stop solution, 10 mL

Information d'application

Plaque: Pre-coated

Protocole: Sandwich ELISA quantitative detection kit for Human TNFRSF18/GITR in cell culture supernates, serum and plasma (heparin, EDTA).Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), also called GITR or AITR is a protein that in humans is encoded by the TNFRSF18 gene. This gene is mapped to 1p36.33. This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Restrictions: For Research Use only

Stockage

Stock: 4 °C/-20 °C

Détail du antigène

Antigène: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Autre désignation: TNFRSF18/GITR (TNFRSF18 Produits)

Synonymes: GITR Kit ELISA, TNFRSF18 Kit ELISA, AITR Kit ELISA, Gitr Kit ELISA, CD357 Kit ELISA, GITR-D Kit ELISA, TNF receptor superfamily member 18 Kit ELISA, tumor necrosis factor receptor superfamily, member 18 Kit ELISA, TNFRSF18 Kit ELISA, Tnfrsf18 Kit ELISA

ID gène: 8784

UniProt: Q9Y5U5

Pathways: Cancer Immune Checkpoints